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OralDNA® Lab Testing

Some patients clean and floss perfectly and still have bleeding gums. Others get cavities no matter how careful they are. The reason isn't always visible, but it's identifiable.

Dental Operatory

A Different Level of Diagnostic Care

We believe great dentistry starts with understanding the why. For most patients, a comprehensive exam, X-rays, and routine cleaning are enough to find that answer.
For others, the same problems keep coming back: recurring decay, persistent bleeding gums, peri-implant inflammation, unexplained sensitivity. When that happens, the answer isn't usually "clean harder" or "floss more." The answer is figuring out what's actually living in your mouth and how your body is responding to it.
That's what OralDNA® Lab Testing tells us.
iTero scanner
iTero scanner

How It Works

OralDNA testing uses a simple oral rinse. You swish a saline solution for 30 seconds and spit into a sealed collection tube. We send it to OralDNA's clinical lab in New York, and within 5–14 business days we receive a detailed report on the bacteria, viruses, fungi, or genetic markers in your mouth.

No blood draw. No biopsy. No discomfort. Just one rinse during your visit.

What We Can Test For

We work with the full OralDNA test menu. Each test is ordered for a specific clinical reason, and we discuss the recommendation with you before any test is run.

Test
What It Identifies
Turnaround
MyPerioPath®
11 bacteria known to cause gum disease and threaten overall health
5 business days
MyPerioID® IL-6
Genetic marker for inflammatory response (IL-6)
5 business days
Alert2™
Combined bacteria + genetics panel (MyPerioPath + MyPerioID)
5 business days
OraRisk® Caries
3 cavity-causing bacteria, type and concentration
7 business days
OraRisk® HPV
50 HPV genotypes linked to oral cancers
5 business days
OraRisk® Candida
9 fungal Candida species
5 business days
OraRisk® HSV
Herpes simplex virus types 1 and 2
5 business days
Celsus One™
8 gene markers tied to inflammatory response
14 business days

What We Can Test For

We work with the full OralDNA test menu. Each test is ordered for a specific clinical reason, and we discuss the recommendation with you before any test is run.

What It Identifies
Turnaround
11 bacteria known to cause gum disease and threaten overall health
5 business days
MyPerioPath®
MyPerioID® IL-6
What It Identifies
Turnaround
Genetic marker for inflammatory response (IL-6)
5 business days
Alert2™
What It Identifies
Traditional Insurance
Combined bacteria + genetics panel (MyPerioPath + MyPerioID)
5 business days
OraRisk® Caries
What It Identifies
Traditional Insurance
3 cavity-causing bacteria, type and concentration
7 business days
OraRisk® HPV
What It Identifies
Traditional Insurance
50 HPV genotypes linked to oral cancers
5 business days
OraRisk® Candida
What It Identifies
Traditional Insurance
9 fungal Candida species
5 business days
OraRisk® HSV
What It Identifies
Traditional Insurance
Herpes simplex virus types 1 and 2
5 business days
Celsus One™
What It Identifies
Traditional Insurance
8 gene markers tied to inflammatory response
14 business days
OralDNA® Lab Testing
OralDNA® Lab Testing

Who Benefits From OralDNA Testing

Testing isn't for everyone. We typically recommend it for patients who:

Have persistent gum inflammation despite good home care

Have a history of recurrent cavities even with regular cleanings

Have a dental implant and want to monitor peri-implant health

Have a family history of severe gum disease

Have systemic conditions (diabetes, heart disease) where oral bacteria matter

Want a baseline assessment of their oral microbiome before major treatment

Why This Matters

Routine cleaning removes plaque. Scaling and root planing removes deep deposits. Both are important. Neither tells us which bacteria are driving disease in your specific mouth, or whether your genetics make you more vulnerable to inflammation.

When we know that, we can:

  • Target the exact pathogens causing your problem with the right antimicrobial

  • Adjust your recall interval based on real risk, not a default schedule

  • Coordinate with your physician when oral bacteria are a factor in systemic health

  • Track whether treatment is actually working at the bacterial level — not just visually

This is what we mean when we say we treat the why. Two patients with similar X-rays can have completely different oral microbiomes — and they need completely different treatment.

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Curious whether OralDNA testing is right for you?

We'll discuss it during your comprehensive exam — no pressure, no obligation. We only recommend testing when it would meaningfully change your treatment.

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